Accumulation of L-type Bovine Prions in Peripheral Nerve Tissues

نویسندگان

  • Yoshifumi Iwamaru
  • Morikazu Imamura
  • Yuichi Matsuura
  • Kentaro Masujin
  • Yoshihisa Shimizu
  • Yujing Shu
  • Megumi Kurachi
  • Kazuo Kasai
  • Yuichi Murayama
  • Shigeo Fukuda
  • Sadao Onoe
  • Ken’ichi Hagiwara
  • Yoshio Yamakawa
  • Tetsutaro Sata
  • Shirou Mohri
  • Hiroyuki Okada
  • Takashi Yokoyama
چکیده

We recently reported the intraspecies transmission of L-type atypical bovine spongiform encephalopathy (BSE). To clarify the peripheral pathogenesis of L-type BSE, we studied prion distribution in nerve and lymphoid tissues obtained from experimentally challenged cattle. As with classical BSE prions, L-type BSE prions accumulated in central and peripheral nerve tissues.

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عنوان ژورنال:

دوره 16  شماره 

صفحات  -

تاریخ انتشار 2010